Schizophrenia-Like Psychosis and Dandy-Walker Variant Comorbidity: Case Report

Psychiatry Investigation 2014³â 11±Ç 1È£ p.102 ~ p.104

(Zincir Selma Bozkurt) - Erenkoy Training and Research Hospital for Psychiatric and Neurological Disorders
(K©¥v©¥lc©¥m Yig¢¨ it) - Erenkoy Training and Research Hospital for Psychiatric and Neurological Disorders
(I¢«zci Filiz) - Erenkoy Training and Research Hospital for Psychiatric and Neurological Disorders
(Semiz Umit Basar) - Erenkoy Training and Research Hospital for Psychiatric and Neurological Disorders

Abstract

Dandy-Walker variant is a developmental malformation consisting of cerebellar hypoplasia and cystic dilatation of the fourth ventricle. Previous research has proposed a possible role for the cerebellum in cognition and in schizophrenia. In this paper we report a schizophrenia-like psychotic disorder in a 30 year-old woman with Dandy-Walker variant. The patient was treated with risperidone 6 mg/day, biperiden 4 mg/day and risperidone depot 50 mg injections fortnightly, and most of the symptoms were ameliorated within 2 months. The similar cognitive profile to populations with cerebellar pathology and rarity of the condition strongly suggests that there may be direct relationship between cerebellar pathology and appearence of psychotic symptoms.

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Schizophrenia, Dandy-Walker, Cerebellum, Comorbidity
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